The main aim of the project is to develop new concepts for a better understanding of health-environment (or gene-environment) interactions in the etiology of exposure related Non-communicable diseases (NCD) and to enhance the complementarity
and synergy between the separate disciplines giving attention to the joint development of skills in interdisciplinary problem-solving.
This action aims to contribute to the development of successful preventive health strategies in European countries.
Project funding:
COST actions
Project results:
1. List of possible exposure modeling methods for environmental and occupational exposure and the basic information needed for good performance was compiled and agenda for the development of different approaches how to validate the exposure assessment methods was developed indicating important key gaps with regard
to exposure assessment for externally caused diseases (performance, availability, usability, feasibility).
2. Generic approach for data mining of toxicity information on environmental factors (human data, population-based studies, animal data, in vitro data, etc…) was developed which is aimed at clear prioritization of measures to mitigate the human
health risk of factors that contribute to the prevalence of morbidity of NCD and to
achieve a higher level of protection.
3. Robust and reproducible automated scoring system leading to improvements in the sensitivity and accuracy of the determination using genotoxicity biomarkers by
overcoming many of the problems caused by subjective evaluation was developed for the monitoring of environmentally/occupationally exposed human populations (i.e. showing an increase of DNA and chromosomal damage in patients with cancer, neurodegenerative syndromes, cardiovascular diseases, and diabetes).
Period of project implementation: 2016-04-11 - 2020-04-10
Project partners: Denmark, Netherlands, Portugal, Romania, Serbia, Turkey, Belgium, Croatia, France, Germany, Hungary, Ireland, Israel, Malta, Norway, Slovenia, Spain, Sweden, Switzerland
